Edenderry Rugby Football Club were founded in 1951 in Edenderry, County Offaly. They first started playing on a rugby pitch given to them near the town's golf course. In 1969, Edenderry won the Leinster Provincial Towns Cup for the first time when they defeated Drogheda in the final at Balreask Old(Navan), shortly after the victory, the club decided to move grounds across the county border to Carbury in County Kildare with a new clubhouse being constructed in 1974 and extended in 1986. In 1983 Edenderry won their second Leinster Provincial Towns Cup by defeating Athy in the final at Spollanstown (Tullamore).

A further fundraising effort to improve the clubhouse was spearheaded by Moss Keane who played with a team of Irish internationals against an Edenderry XV in a charity match in 1990. The renovations were finished in 1999 with the Irish Minister of Finance, Charlie McCreevy and the President of the Irish Rugby Football Union, Billy Lavery opening it.

A senior ladies team was formed in 2010 which proved just as successful with the Leinster Cup being won for the first time in 2012 when New Ross were defeated in the final at Westmanstown (Garda), the success continued to follow the ladies teams with a second Leinster Cup added in 2016 when Tullamore were defeated in the final at Silken Thomas Park (Cill Dara), this win secured the second half of a double as the League had been added weeks earlier when Edenderry defeated Rathdrum in the final after extra time at Donnybrook Stadium.

Edenderry have been used as hosts for the Provincial Towns Cup Final in 2011 and again in 2013. They have also hosted training sessions for the Leinster Rugby provincial side.

In 2016 the club was in a position to erect Match Quality Lights on its main playing pitch, the project was funded through a Drehid Application Scheme and A "Sponsor a Light" Donation Board with over 90 pledges coming from Club Members and Local Businesses.

In 2019, the IRFU selected Edenderry to host the final of the national All-Ireland Junior Cup.